In Vitro Metabolite Identification

- Y. Zhu, G. Chen, K. Zhang, C. Chen, W. Chen, M. Zhu, H. Jiang. High-Throughput Metabolic Soft-Spot Identification in Liver Microsomes by LC/UV/MS: Application of a Single Variable Incubation Time Approach. Molecules (Basel, Switzerland). 2022;27(22).

- J. Carlier, X. Diao, R. Giorgetti, F. P. Busardò, M. A. Huestis. Pyrrolidinyl Synthetic Cathinones α-PHP and 4F-α-PVP Metabolite Profiling Using Human Hepatocyte Incubations. International journal of molecular sciences. 2020;22(1).

- C. Tang, Z. Chen, X. Dai, W. Zhu, D. Zhong, X. Chen. Mechanism of Reductive Metabolism and Chiral Inversion of Proton Pump Inhibitors. Drug metabolism and disposition: the biological fate of chemicals. 2019;47(6):657-64.

- X. Diao, M. A. Huestis. New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites. Frontiers in chemistry. 2019;7:109.

- X. Diao, J. Carlier, M. S. Zhu, M. A. Huestis. Metabolism of the new synthetic cannabinoid EG-018 in human hepatocytes by high-resolution mass spectrometry. Forensic toxicology. 2018;36(2):304-12.

- J. Carlier, X. Diao, M. A. Huestis. Synthetic cannabinoid BB-22 (QUCHIC): Human hepatocytes metabolism with liquid chromatography-high resolution mass spectrometry detection. Journal of pharmaceutical and biomedical analysis. 2018;157:27-35.

- X. Diao, J. Carlier, M. Zhu, M. A. Huestis. Human Hepatocyte Metabolism of Novel Synthetic Cannabinoids MN-18 and Its 5-Fluoro Analog 5F-MN-18. Clinical chemistry. 2017;63(11):1753-63.

- X. Diao, K. B. Scheidweiler, A. Wohlfarth, S. Pang, R. Kronstrand, M. A. Huestis. In Vitro and In Vivo Human Metabolism of Synthetic Cannabinoids FDU-PB-22 and FUB-PB-22. The AAPS journal. 2016;18(2):455-64.

- G. Chen, Z. Cheng, K. Zhang, H. Jiang, M. Zhu. An integrated approach for profiling oxidative metabolites and glutathione adducts using liquid chromatography coupled with ultraviolet detection and triple quadrupole-linear ion trap mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2016;129:482-91.

- X. Zhuo, W. Zhao, J. Zheng, W. G. Humphreys, Y. Z. Shu, M. Zhu. Bioactivation of coumarin in rat olfactory mucosal microsomes: Detection of protein covalent binding and identification of reactive intermediates through analysis of glutathione adducts. Chemico-biological interactions. 2009;181(2):227-35.

- H. Zhang, D. Zhang, K. Ray, M. Zhu. Mass defect filter technique and its applications to drug metabolite identification by high-resolution mass spectrometry. Journal of mass spectrometry : JMS. 2009;44(7):999-1016.