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In Vitro Metabolite Identification of Small Molecule Drugs

Biotransformation of slowly metabolized drugs in 3D hepatocyte spheroid culture
Comparative metabolism across species in liver microsomes, hepatocytes and other in vitro systems
GSH-trapping of reactive metabolites in liver microsomes
Metabolic stability analysis and metabolite profiling in liver microsomes, hepatocytes and other in vitro systems
Metabolic soft spot analysis in liver microsomes, hepatocytes and other in vitro systems
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In Vitro Metabolite Identification of Small Molecule Drugs
In Vivo Metabolism and Disposition of Small Molecule Drugs
Radiolabeled ADME Studies in Animals and Humans
ADME Studies of Antibody-Drug Conjugates (ADCs)
Biotransformation of New Drug Modalities
Metabolizing Enzyme Phenotyping
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